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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err assisting caution and allow FDA do its job and demand some study be done in order that the public understands the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on their medications.

Researchers discovered that participants investing in this drug for the year, dropped a few pounds within four weeks and have kept the load off through the 56 weeks from the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more effective and safer.

Combo-pilling is the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise hypertension and heartrate, and must not be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure and pulse rate and must not be used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients on the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.


An independent report published by Gant Daily in April also stated that naltrexone also works best for kleptomaniacs and gambling addicts, also. Citing research from the University of Minnesota School of Medicine, Gant Daily reported the drug conditions kleptomaniacs and chronic gamblers in the same manner with alcohol and opioid addicts'by blocking the effects of endorphins, that your brain releases when experiencing craving or compulsions.